Pandora’s Box? The Risks of Pathogen Escape from Laboratories

Laboratory procedures for working on dangerous pathogens has changed significantly over the past 40 years. Randal J. Schoepp

Laboratory procedures for working on dangerous pathogens has changed significantly over the past 40 years. Randal J. Schoepp, James Gathany

Pathogens are maintained in laboratories around the world for many reasons. They can be used to develop vaccines, to provide materials for diagnostic tests, or to study genomes, offering clues as to how pathogens may evolve so that we are better prepared to deal with them.

There is debate within the scientific community as to exactly what kinds of research should be done on especially nasty organisms commonly called Potential Pandemic Pathogens, such as the deadly SARS respiratory virus or highly pathogenic avian influenza viruses. Some believe the risks of escape, though small, are not worth taking as an accidental release could sicken or even kill millions of people, animals, or both.

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New Kid on the Block: H7N9 Set to Become Deadliest Avian Influenza Virus in People

Human cases of H7N9 avian influenza virus FAO

Human cases of H7N9 avian influenza virus          FAO

A new avian influenza virus now rivals H5N1 as a candidate for the potential cause of a human pandemic one day. H7N9 first appeared in people three years ago and shares many characteristics with H5N1. But some key differences make this newer virus more difficult to keep tabs on as it circulates quietly through poultry flocks.

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